Generic Plavix (clopidogrel bisulfate).
Plavix is used in the treatment of strokes and heart attacks in patients who are at a high risk. In a study, it was found that Plavix was more effective than aspirin at reducing the possibility of a heart attack, and reduces the level of stomach and intestinal bleeding often associated with aspirin and Plavix. An anti-platelet drug, it works by inhibiting the ability of the platelets to clump together, forming a blood clot, but does not cause a serious reduction in white blood cells so regular white blood cell count testing is not required during treatment.
If you have a recent history of strokes or heart attacks, or of peripheral vascular disease (atherosclerotic arterial disease or “hardening” of the arteries which increases the risk of further heart problems, taking Plavix can be used to reduce the potential risk.
METOD OF USE
It is recommended, and as directed by your doctor or physician, that Plavix is taken orally with or without food, but with a full glass of water (approx 240ml). If you miss a dose of Plavix, take a tablet as soon as you remember, unless this is close to your next scheduled dose. If it is, miss that dose and then return to your regular dosing schedule. Do not take 2 doses at once.
Plavix is to be stored at room temperature, between 59°F and 86°F (15-30°C), in its original container, tightly closed and away from heat, light and moisture. Do not store Plavix in the bathroom. The product must be kept out of the reach of children and pets at all times. Any medication that is out of date should be disposed of safely (any pharmacist will be able to advise you on disposal instructions).
If you are due to undergo any surgical procedures, advise your doctor or dentist immediately that you are taking this medication.
If you are taking Plavix, do not take any of the following without consulting your doctor:
- ibuprofen (Motrin, Advil, Nuprin and others);
- naproxen (Aleve, Anaprox, Naprosyn and others);
- ketoprofen (Orudis, Orudis KT, Oruvail);
- indomethacin (Indocin);
- nabumetone (Relafen);
- oxaprozin (Daypro); or
- any other non-steroidal anti-inflammatory medications (NSAIDs).
Advise your doctor as soon as possible if you suffer from any unusual bleeding or bruising. It is also advised that it may take longer than normal for any bleeding to stop, even with minor wounds.
Studies have shown that Plavix appears in breast milk, but it is not known whether it appears in human breast milk. Therefore, any woman breast feeding should consult their doctor as soon as possible to discuss the potential risks and side effects prior to taking Plavix.
POTENTIAL SIDE EFFECTS
Plavix has a similar tolerability level to aspirin. Diarrhea, a rash or itching occurs in 1 in 20 patients, and abdominal pain in 1 in 20 patients, which is less frequent than taking aspirin. A similar antiplatelet medication, Ticlopidine (ticlid), has been associated with a reduction in white blood cell count in approximately 0.8% to 1% of patients. This risk is reduced to 0.4% of patients with Plavix, but this is higher than with aspirin.
In 1 out of every 250,000 patients, Plavix can cause a condition known as thrombotic thrombocytopenic purpura (TTP). This is a serious condition where blood clots form throughout the body. The blood platelets that are part of clotting are consumed, and can result in bleeding due to the reduced number of platelets in the body. It is noted that Ticlopidine (ticlid) causes a higher rate of TTP than Plavix, by approximately 17-50 times more frequently.
If you experience any of the above or following side effects, stop taking Plavix, seek immediate emergency medical treatment and notify your doctor as soon as possible. Possible side effects include:
- an allergic reaction, such as rash, hives or itching;
- breathing difficulties, sore or swelling in the throat;
- swelling of the lips, face, tongue or mouth;
- black or bloody vomit or stools, upset stomach, diarrhea or constipation;
- headache, confusion or dizziness;
- unusual bruising or bleeding; or
- a bleeding nose.
Do not share Plavix with anyone else. It is recommended that you always complete a prescribed course. Do not use Plavix at a later date for a different medical reason, unless advised by your doctor.
lease note that the above list is not complete and other side effects may occur. Should any other side effects happen, consult your doctor as soon as possible.Plavix 2011-2014.